Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibits platelet aggregation and thus inhibits aspects of blood clotting used to treat patients with acute coronary syndrome, myocardial infarction (MI), peripheral vascular disease and some stroke (ischemic type) patients. Clopidogrel, sold under the trade name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy). It is taken by mouth. Onset of effects is. Plavix (clopidogrel) prevents platelets in your blood from sticking together to form an unwanted blood clot that could block an artery. Plavix is used to lower your risk of having a stroke, blood clot, or serious heart problem after you've had a heart attack, severe chest pain , or circulation problems. My cardiologists suggested I read about the DAPT trials in regards to Plavix-aspirin therapy and the length of therapy. I had 2 des, which are first generation, 15 months ago. Plavix is the brand name form of the generic drug clopidogrel bisulfate, an anti-platelet medication that's used to prevent blood clots. Blood clots can form in blood as a result of certain heart. CAPRIE (Plavix vs Aspirin) In CAPRIE, gastrointestinal hemorrhage occurred at a rate of 2.0% in those taking Plavix versus 2.7% in those taking aspirin; bleeding requiring hospitalization occurred in 0.7% and 1.1%, respectively. I have been taking plavix since 2001, and I want to know if this is necessary and/or safe. My family doctor said I need to take plavix because I have small vessels in my brain. Learn about Plavix (Clopidogrel Bisulfate) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. If you’re one of the 35 million Americans who suffer from hay fever, read on for what plants are to blame, where to find them and how to get relief. Questions about dosage and length of treatment with Plavix (clopidogrel), Effient (prasugrel), and aspirin after having a stent? Have you experienced allergic reactions or side-effects? Join the conversation.